Program-space Diffusion for Morphology-to-Transcriptomics Prediction

Excerpt

arXiv:2608.14330v1 Announce Type: new Abstract: Spatial transcriptomics (ST) enables genome-wide gene expression profiling while preserving tissue architecture, but its cost and limited scalability remain major bottlenecks. This has motivated models that predict spatial expression directly from routine histology. Despite promising results, most existing approaches operate at the gene level without leveraging established transcriptomic modeling practices and rely on heterogeneous gene selection s