Synthesizing Post-Acetazolamide Cerebral Blood Flow Maps from Baseline MRI in Moyamoya Using 3D Generative AI

Excerpt

arXiv:2608.14758v1 Announce Type: cross Abstract: For patients with Moyamoya disease, impaired cerebrovascular reserve (CVR) is an important hemodynamic criterion for recommending extracranial-to-intracranial bypass surgery. Standard CVR assessment in this cohort uses paired arterial spin labeling (ASL) perfusion MRI acquired before and after acetazolamide (ACZ). When ACZ is contraindicated or avoided, the post-ACZ cerebral blood flow (CBF) map needed for hemodynamic assessment is unavailable. W