Ranking-Aware Prompt Optimization for Multimodal Clinical Diagnosis

Excerpt

arXiv:2609.40361v1 Announce Type: new Abstract: Multimodal large language models (MLLMs) are rapidly advancing clinical diagnosis, yet their adaptation pipelines remain anchored to accuracy-based objectives. Clinical data are heavily class-imbalanced: a constant-majority predictor can score above 90% accuracy while being clinically useless. We therefore evaluate and optimize for AUROC, a threshold-free score that ranks positives above negatives and is invariant to class balance. We focus on prom