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arXiv cs.AIOctober 7, 2026

An LLM-in-the-loop RL Framework for Bioinformatics Feature Selection

Excerpt

arXiv:2610.05600v1 Announce Type: cross Abstract: High-dimensional bioinformatics data, characterized by a large number of features relative to the number of samples, pose major challenges such as the ``curse of dimensionality,'' leading to overfitting, high computational cost, and poor generalization. Traditional feature selection methods often suffer from limited scalability and adaptability in such domains. We propose an LLM-in-the-loop reinforcement learning (RL) framework for bioinformatics